Botox or the new face of the fight against depression - literature review

Introduction: Depression is a common psychiatric disorder leading to high burden especially for some other comorbidity. Annually over 43 billion dollars are expended patients with depression among them 28% directly and costs related mortality morbidity due depression. The aim of the study: Paying attention new options treating – disease that affects more people.Material method: research was done by usage PubMed Google Scholar articles about topic of: botulinum toxin; depression; treatment.Description state knowledge: Injecting Botox into muscles responsible expression anguish or sadness may potentially decrease experience feelings. reversibly blocks acetylcholine release from neuronal axons synapse, inhibiting neuromuscular transmission. If facial feedback hypothesis correct, injecting corrugator procerus muscles, it will inhibit frown expressions have capability propagating enhancing sad depressed feelings.Summary: results all randomized control trials proved toxin A injection in glabellar region associated significant improvement mood be safe effective treatment reduce symptoms